This product is for research use only, not for human use. We do not sell to patients.
| Size | Price | Stock |
|---|---|---|
| 250mg | $1235 | Check With Us |
| 500mg | $1935 | Check With Us |
| 1g | $2905 | Check With Us |
: Cat #: V3967 CAS #: 1219739-36-2 Purity ≥ 98%
Description: EX229 (EX-229; AMPK Activator 991), a benzimidazole analog, is a novel, potent and allosteric AMPK (AMP-activated protein kinase) activator with Kd values of 0.06 μM, 0.06 μM and 0.51 μM for α1β1γ1, α2β1γ1 and α1β2γ1 in biolayer interferometry, respectively.
References: Xiao B, et al. Structural basis of AMPK regulation by small molecule activators. Nat Commun. 2013;4:3017.
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- Physicochemical and Storage Information
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- Related Biological Data
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- Quality Control Documentation
| Molecular Weight (MW) | 431.87 |
|---|---|
| Molecular Formula | C₂₄H₁₈ClN₃O₃ |
| CAS No. | 1219739-36-2 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: >10 mg/mLr |
| Water: <1 mg/mLr | |
| Ethanol: <1 mg/mL | |
| SMILES Code | O=C(O)C1=CC(OC2=NC3=CC(Cl)=C(C4=CC5=C(N(C)C=C5)C=C4)C=C3N2)=CC=C1C |
| Synonyms | EX229; EX 229; EX-229; AMPK Activator 991 |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.3155 mL | 11.5776 mL | 23.1551 mL | 46.3102 mL |
| 5mM | 0.4631 mL | 2.3155 mL | 4.6310 mL | 9.2620 mL |
| 10mM | 0.2316 mL | 1.1578 mL | 2.3155 mL | 4.6310 mL |
| 20mM | 0.1158 mL | 0.5789 mL | 1.1578 mL | 2.3155 mL |
This equation is commonly abbreviated as: C1 V1 = C2 V2
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.