6-Gingerol
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $285 | Check With Us |
| 250mg | $460 | Check With Us |
| 500mg | $690 | Check With Us |
: Cat #: V9698 CAS #: 23513-14-6 Purity ≥ 99%
Description: 6-Gingerol is a novel and potent active constituent of fresh ginger.
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| Molecular Weight (MW) | 294.39 |
|---|---|
| Molecular Formula | C17H26O4 |
| CAS No. | 23513-14-6 |
| SMILES Code | CCCCC[C@H](O)CC(CCC1=CC=C(O)C(OC)=C1)=O |
| Synonyms | 6-Gingerol |
| Protocol | In Vitro | [6]-gingerol inhibits colon cancer cell proliferation and induced apoptosis, while the normal colon cells are unaffected. [6]-gingerol down-regulates phorbol myristate acetate induced phosphorylation of ERK1/2 and JNK MAP kinases and activation of AP-1 transcription factor, but has only little effects on phosphorylation of p38 MAP kinase and activation of NF-kappa B. |
|---|---|---|
| In Vivo | In animal studies, [6]-gingerol significantly ameliorates DSS-induced colitis by restoration of body weight loss, reduction in intestinal bleeding, and prevention of colon length shortening. In addition, [6]-gingerol suppresses DSS-elevated production of proinflammatory cytokines (IL-1β, TNFα, and IL-12). |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.3969 mL | 16.9843 mL | 33.9685 mL | 67.9371 mL |
| 5mM | 0.6794 mL | 3.3969 mL | 6.7937 mL | 13.5874 mL |
| 10mM | 0.3397 mL | 1.6984 mL | 3.3969 mL | 6.7937 mL |
| 20mM | 0.1698 mL | 0.8492 mL | 1.6984 mL | 3.3969 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
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Volume
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Molecular Weight*
The dilution calculator equation
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Volume(start)
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This equation is commonly abbreviated as: C1 V1 = C2 V2
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Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.