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Phenformin HCl (ST50409947; D08352; W104144)

This product is for research use only, not for human use. We do not sell to patients.

Phenformin HCl (ST50409947; D08352; W104144)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
25g$380Check With Us
50g$550Check With Us
100g$825Check With Us

Cat #: V0247 CAS #: 834-28-6 Purity ≥ 98%

Description: Phenformin HCl (ST-50409947; D-08352; W-104144), the hydrochloride salt of phenformin, was a marketed anti-diabetic drug of the biguanide class, but was withdrawn from most markets in the late 1970s due to a high risk of lactic acidosis.

References: Sakamoto K, et al. Activity of LKB1 and AMPK-related kinases in skeletal muscle: effects of contraction, phenformin, and AICAR. Am J Physiol Endocrinol Metab.?2004 Aug;287(2):E310-7.

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Product Promise

Promise
Molecular Weight (MW)241.72
Molecular FormulaC10H16ClN5
CAS No.834-28-6
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 48 mg/mL (198.6 mM)r
Water: 48 mg/mL (198.6 mM)r
Ethanol: 12 mg/mL (49.6 mM)
SMILES CodeC1=CC=C(C=C1)CCN=C(N)N=C(N)N.Cl
SynonymsPhenformin HCl; Meltrol; Dipar; Phenethylbiguanide hydrochloride; W-104144; ST-50409947; D-08352; W104144; ST50409947; D08352; W 104144; ST 50409947; D 08352; Phenformin Hydrochloride;
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM4.1370 mL20.6851 mL41.3702 mL82.7404 mL
5mM0.8274 mL4.1370 mL8.2740 mL16.5481 mL
10mM0.4137 mL2.0685 mL4.1370 mL8.2740 mL
20mM0.2069 mL1.0343 mL2.0685 mL4.1370 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.