BVT948
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $1300 | To Be Confirmed |
| 200mg | $1950 | To Be Confirmed |
| 500mg | $3290 | To Be Confirmed |
: Cat #: V17300 CAS #: 39674-97-0 Purity ≥ 99%
Description: BVT948 (BVT-948) is a novel and potent protein tyrosine phosphatases (PTP) inhibitor with IC50 of 0.09 - 1.7 μM.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 241.24 |
|---|---|
| Molecular Formula | C14H11NO3 |
| CAS No. | 39674-97-0 |
| SMILES Code | O=C(C(C)(C)C1=C2O)N=C1C3=CC=CC=C3C2=O |
| Synonyms | BVT948; BVT-948; BVT 948; SPS8I3; SPS-8I3; SPS 8I3; |
| Protocol | In Vitro | Results show that the effect of BVT948 (BVT.948) is to strengthen the insulin signal and has no effects on the duration of the signal. BVT948 appears to be an effective inhibitor of both protein tyrosine phosphatases (PTP activity and P450 activity. |
|---|---|---|
| In Vivo | Results show that 3 μmol/kg BVT948 (BVT.948) significantly enhances glucose clearance from the blood stream in response to insulin compare with vehicle-treated controls. |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 4.1452 mL | 20.7262 mL | 41.4525 mL | 82.9050 mL |
| 5mM | 0.8290 mL | 4.1452 mL | 8.2905 mL | 16.5810 mL |
| 10mM | 0.4145 mL | 2.0726 mL | 4.1452 mL | 8.2905 mL |
| 20mM | 0.2073 mL | 1.0363 mL | 2.0726 mL | 4.1452 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.