BR-1

This product is for research use only, not for human use. We do not sell to patients.

BR-1
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$450Check With Us
500mg$750Check With Us
1g$1125Check With Us

Cat #: V13084 CAS #: 893449-38-2 Purity ≥ 99%

Description: BR-1 is a novel and potent PRL-3 inhibitor (IC50 = 0.9 μM) with anticancer activity.

References: Ahn JH, et al. Synthesis and biological evaluation of rhodanine derivatives as PRL-3 inhibitors. Bioorg Med Chem Lett. 2006;16(11):2996-2999.

Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products

Product Promise

Promise
Molecular Weight (MW)485.21
Molecular FormulaC17H11Br2NO2S2
CAS No.893449-38-2
SMILES CodeO=C1NC(S/C1=C/C2=CC(Br)=CC=C2OCC3=CC=CC=C3Br)=S
SynonymsBR1; BR 1; BR-1; PRL-3 Inhibitor I
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.0610 mL10.3048 mL20.6096 mL41.2193 mL
5mM0.4122 mL2.0610 mL4.1219 mL8.2439 mL
10mM0.2061 mL1.0305 mL2.0610 mL4.1219 mL
20mM0.1030 mL0.5152 mL1.0305 mL2.0610 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.