PTP1B-IN-2

This product is for research use only, not for human use. We do not sell to patients.

PTP1B-IN-2
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$1250Check With Us
500mg$1650Check With Us
1g$2475Check With Us

Cat #: V2845 CAS #: 1919853-46-5 Purity ≥ 98%

Description: PTP1B-IN-2 is a potent and selective protein tyrosine phosphatase-1B (PTP1B) inhibitor.

References: Liu P, et al. Discovery of novel, high potent, ABC type PTP1B inhibitors with TCPTP selectivity and cellular activity. Eur J Med Chem. 2016 Aug 8;118:27-33.

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Product Promise

Promise
Molecular Weight (MW)680.78
Molecular FormulaC34H36N2O9S2
CAS No.1919853-46-5
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: ≥100 mg/mLr
Water: <1 mg/mLr
Ethanol: <1 mg/mL
SMILES CodeO=S(N(CC1=CC=C(C=C1)N(CC(OC)=O)S(C)(=O)=O)C(C=C2)=CC=C2OCC3=CC(C(OC)=O)=C(C)C=C3)(CC4=CC=CC=C4)=O
SynonymsPTP1B-IN-2; PTP1B-IN-2; PTP1B-IN-2
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.4689 mL7.3445 mL14.6890 mL29.3781 mL
5mM0.2938 mL1.4689 mL2.9378 mL5.8756 mL
10mM0.1469 mL0.7345 mL1.4689 mL2.9378 mL
20mM0.0734 mL0.3672 mL0.7345 mL1.4689 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.