Verdiperstat (AZD-3241)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 250mg | $750 | Check With Us |
| 500mg | $1250 | Check With Us |
| 1g | $1875 | Check With Us |
: Cat #: V4275 CAS #: 890655-80-8 Purity ≥ 98%
Description: Verdiperstat (also known as AZD3241) is a novel, potent, selective, irreversible and orally bioactive myeloperoxidase/MPO inhibitor (IC50 = 630 nM) with the potential to be used in the treatment of neurodegenerative brain disorders.
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| Molecular Weight (MW) | 253.32 |
|---|---|
| Molecular Formula | C11H15N3O2S |
| CAS No. | 890655-80-8 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| SMILES Code | O=C(N1)C(NC=C2)=C2N(CCOC(C)C)C1=S |
| Synonyms | AZD-3241; AZD 3241; AZD3241; Verdiperstat; CAS#890655-80-8 |
| Protocol | In Vitro | Verdiperstat (AZD3241) is a myeloperoxidase (MPO) inhibitor, with an IC50 of 630 nM, and is used in the research of neurodegenerative brain disorders. |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.9476 mL | 19.7379 mL | 39.4758 mL | 78.9515 mL |
| 5mM | 0.7895 mL | 3.9476 mL | 7.8952 mL | 15.7903 mL |
| 10mM | 0.3948 mL | 1.9738 mL | 3.9476 mL | 7.8952 mL |
| 20mM | 0.1974 mL | 0.9869 mL | 1.9738 mL | 3.9476 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start)
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Volume(start)
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Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
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C1
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V1
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C2
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Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.