GSK-3 inhibitor 1
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $1800 | Check With Us |
| 250mg | $2980 | Check With Us |
| 500mg | $4470 | Check With Us |
: Cat #: V3531 CAS #: 603272-51-1 Purity ≥ 98%
Description: GSK-3 inhibitor 1 is a novel and potent inhibitor of GSK-3 (Glycogen synthase kinase-3).
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| Molecular Weight (MW) | 437.85 |
|---|---|
| Molecular Formula | C₂₂H₁₇ClFN₅O₂ |
| CAS No. | 603272-51-1 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| SMILES Code | FC1=CC(CNCC2)=C(N2C=C3C4=C(C5=CN=C6N5C=CC=C6)C(NC4=O)=O)C3=C1.Cl |
| Synonyms | GSK-3 inhibitor 1; GSK 3 inhibitor 1 |
| Protocol | In Vitro | GSK-3 inhibitor 1 can be used to induce, promote or enhance the growth, proliferation or regeneration of inner ear tissues such as inner ear supporting cells or inner ear hair cells. |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.2839 mL | 11.4194 mL | 22.8389 mL | 45.6777 mL |
| 5mM | 0.4568 mL | 2.2839 mL | 4.5678 mL | 9.1355 mL |
| 10mM | 0.2284 mL | 1.1419 mL | 2.2839 mL | 4.5678 mL |
| 20mM | 0.1142 mL | 0.5710 mL | 1.1419 mL | 2.2839 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.