CTPI-2
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 500mg | $250 | Check With Us |
| 1g | $400 | Check With Us |
| 5g | $1010 | Check With Us |
: Cat #: V9925 CAS #: 68003-38-3 Purity ≥ 99%
Description: CTPI-2 is a novel, potent, specific, and third-generation mitochondrial citrate carrier SLC25A1 inhibitor with a KD of 3.5 μM.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 356.74 |
|---|---|
| Molecular Formula | C13H9ClN2O6S |
| CAS No. | 68003-38-3 |
| SMILES Code | COC1=NC(C2=C3OCCOC3=CC=C2)=CC=C1NC4=CC=C(CN(C)C)C=C4 |
| Synonyms | ABD-7; ABD 7; ABD7; RAS inhibitor Abd-7; CTPI-2; CTPI 2; CTPI2; D1W |
| Protocol | In Vivo | CTPI-2 is a unique regulator of glycolysis that limits the metabolic plasticity of cancer stem cells (CSCs). CTPI-2 (26 mg/kg; i.p.) inhibits tumor growth in in vivo models of non-small cell lung cancer (NSCLC). |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.8032 mL | 14.0158 mL | 28.0316 mL | 56.0632 mL |
| 5mM | 0.5606 mL | 2.8032 mL | 5.6063 mL | 11.2126 mL |
| 10mM | 0.2803 mL | 1.4016 mL | 2.8032 mL | 5.6063 mL |
| 20mM | 0.1402 mL | 0.7008 mL | 1.4016 mL | 2.8032 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.