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4′,5-Dihydroxyflavone

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4′,5-Dihydroxyflavone
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Size Price Stock
10g$650Check With Us
25g$1200Check With Us
50g$1800Check With Us

Cat #: V29713 CAS #: 6665-67-4 Purity ≥ 99%

Description: 4',5-Dihydroxyflavone is a flavonoid analog acting as a soybean LOX-1 and yeast α-Glucosidase inhibitor, with an Ki of 102.6 μM for soybean LOX-1 and an IC50 of 66 μM for yeast α-glucosidase.

References: Ribeiro D, et al. Inhibition of LOX by flavonoids: a structure-activity relationship study. Eur J Med Chem. 2014 Jan 24;72:137-45.

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Molecular Weight (MW)254.24
Molecular FormulaC15H10O4
CAS No.6665-67-4
Synonyms4',5-Dihydroxyflavone
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.9333 mL19.6665 mL39.3329 mL78.6658 mL
5mM0.7867 mL3.9333 mL7.8666 mL15.7332 mL
10mM0.3933 mL1.9666 mL3.9333 mL7.8666 mL
20mM0.1967 mL0.9833 mL1.9666 mL3.9333 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.