CAY10698 is a novel and potent 12-LO inhibitor ( IC50 =5.1 µM).

5-Demethylnobiletin is a novel and potent activator of the JNK signaling pathway.

Zileuton (also known as A-64077; Abbott 64077; ZYFLO; ZYFLO CR) is a novel, potent and orally bioactive inhibitor of 5-lipoxygenase, and thus inhibits leukotrienes (LTB4, LTC4, LTD4, and LTE4) formation, it was introduced in 1996 to decrease the symptoms of asthma.

ML 351 is a novel and potent 12/15 LOX inhibitor.

β-Boswellic acid is extracted from the gum resin of Boswellia serrate.

PD146176 (alfo known as NSC168807) is a novel and potent 15-Lipoxygenase (15-LO) inhibitor which inhibits rabbit reticulocyte 15-LO with a Ki of 197 nM.

AKBA, an active triterpenoid isolated from Boswellia serrate, is an antiangiogenic and neuroprotective agent as well as a novel Nrf2 activator.

4-MMPB is a poten and selective 15-lipoxygenase inhibitor ( IC50 =18 μM).

CDC(Cinnamyl-3,4-dihydroxy-α-cyanocinnamate) lipoxygenase inhibitor is a novel ,potent and direct inhibitor of 5-LO (5-Lipoxygenase),12-LO and 15-LO.

4′,5-Dihydroxyflavone is a flavonoid analog acting as a soybean LOX-1 and yeast α-Glucosidase inhibitor, with an Ki of 102.6 μM for soybean LOX-1 and an IC50 of 66 μM for yeast α-glucosidase.