Lithocholic acid

This product is for research use only, not for human use. We do not sell to patients.

Lithocholic acid
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
10g$160Check With Us
50g$499Check With Us
100g$750Check With Us

Cat #: V1843 CAS #: 434-13-9 Purity ≥ 98%

Description: Lithocholic acid (3α-Hydroxy-5β-cholanic acid), a secondary bile acid formed from chenodeoxycholate by bacterial action, acts as a detergent to solubilize fats for absorption and is itself absorbed.

References: Jenkins, D.J., et al., Effect on blood lipids of very high intakes of fiber in diets low in saturated fat and cholesterol. N Engl J Med, 1993. 329(1): p. 21-6.

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Product Promise

Promise
Molecular Weight (MW)376.57
Molecular FormulaC24H40O3
CAS No.434-13-9
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 75 mg/mL (199.2 mM)r
Water: <1 mg/mLr
Ethanol: 47 mg/mL (124.8 mM)
SMILES CodeC[C@H](CCC(O)=O)[C@H]1CC[C@@]2([H])[C@]3([H])CC[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C
SynonymsLithocolic acid; Lithocholate; 3α-Hydroxy-5β-cholanic acid
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.6555 mL13.2777 mL26.5555 mL53.1110 mL
5mM0.5311 mL2.6555 mL5.3111 mL10.6222 mL
10mM0.2656 mL1.3278 mL2.6555 mL5.3111 mL
20mM0.1328 mL0.6639 mL1.3278 mL2.6555 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.