UVI3003
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
Size | Price | Stock |
---|---|---|
250mg | $1100 | Check With Us |
500mg | $1700 | Check With Us |
1g | $2550 | Check With Us |
Cat #: V16574 CAS #: 847239-17-2 Purity ≥ 99%
Description: UVI3003 is a novel and potent RXR antagonist.
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Molecular Weight (MW) | 436.58 |
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Molecular Formula | C28H36O4 |
CAS No. | 847239-17-2 |
SMILES Code | O=C(O)/C=C/C1=CC=C(O)C(C2=C(OCCCCC)C=C3C(C)(C)CCC(C)(C)C3=C2)=C1 |
Synonyms | UVI3003, UVI 3003, UVI-3003 |
Protocol | In Vitro | UVI3003 inhibits the activity of xenopus and human RXRα, with IC50s of 0.22 and 0.24 μM, respectively. UVI3003 fully activates xPPARγ with an EC50 of 12.6 μM, and is almost completely inactive on hPPARγ and mPPARγ. |
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These protocols are for reference only. InvivoChem does not
independently validate these methods.
Solvent volume to be added | Mass (the weight of a compound) | |||
---|---|---|---|---|
Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
1mM | 2.2905 mL | 11.4527 mL | 22.9053 mL | 45.8106 mL |
5mM | 0.4581 mL | 2.2905 mL | 4.5811 mL | 9.1621 mL |
10mM | 0.2291 mL | 1.1453 mL | 2.2905 mL | 4.5811 mL |
20mM | 0.1145 mL | 0.5726 mL | 1.1453 mL | 2.2905 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Concentration
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Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
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Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.