Fenretinide (4-HPR), a synthetic retinoid deriverative, is a novel, potent and orally bioactive synthetic phenylretinamide analogue of retinol (vitamin A) with potential antineoplastic and chemopreventive activities.
Tamibarotene (formerly SY-1425; SY1425; Am 80; Retinobenzoic acid, Amnoid, AMNOLAKE) is a novel, potent, orally bioavailable, and synthetic retinoic acid receptor (RAR) agonist with potential anticancer activity against AML-acute promyelocytic leukaemia.
Tretinoin (Ro-5488; Vitamin A acid; ATRA; TRA; alltrans vitamin A acid; All-trans Retinoic Acid; Avita; Renova; Aberel; Aknoten; RetinA), used to treat acne or other skin disease, is a naturally-occurring acid of retinol and a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR).
Tazarotene (AGN 190168, AGN190168,Tazarotene, Fabior, Zorac; AGN-190168), a third-generation prescription topical retinoid, is a prodrug of tazarotenic acid with selective affinity for RARβ and RARγ.
Adapalene (Differin; Adaferin; CD271; Adapaleno; ADAPALENE; Adapalenum), structurallysimilar to vitamin A, is a synthetic, retinoic acid analog acting as a dual RAR and RXR agonist with potential anticancer activity.
Etretinate (Tegison, Ethyl etrinoate, Retinoid, Etretinato) is an orally bioactive, second-generation, aromatic retinoid acid which is effective in psoriasis and other dermatological syndromes.
UVI3003 is a novel and potent RXR antagonist.
TTNPB (AGN-191183; Ro 13 7410; AGN 191183; Arotinoid Acid, Ro13-7410, AGN191183) is a potent RAR (retinoic acid receptor) agonist with potential antitumor activity.
Bexarotene (Ro26-445; LGD-1069; SR-11247; Ro-26 445; Targretin Ro 26-44) is a synthetic retinoid analog and selective agonist of RXR-retinoid X receptors with potential anticancer chemopreventive, teratogenic and embryotoxic properties.