LY3381916 (IDO1-IN-5)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 250mg | $990 | Check With Us |
| 500mg | $1550 | Check With Us |
| 1g | $2325 | Check With Us |
: Cat #: V4880 CAS #: 2166616-75-5 Purity ≥ 98%
Description: LY-3381916 (LY3381916) is a novel, potent, oral, selective and brain penetrant inhibitor of IDO1 with anticancer activity.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 396.45 |
|---|---|
| Molecular Formula | C₂₃H₂₅FN₂O₃ |
| CAS No. | 2166616-75-5 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| SMILES Code | FC1=CC=C(C(N[C@H](C)C2=CC=C(N(C(C3CCOCC3)=O)CC4)C4=C2)=O)C=C1 |
| Synonyms | LY-3381916; LY 3381916; LY 3381916; IDO1-IN-5; IDO1-IN-5; IDO1 IN-5; IDO1-IN5; IDO1IN5; IDO1 IN5; |
| Protocol | In Vitro | DO1-IN-5 (up to 100 µM) shows no obvious agonism of aryl hydrocarbon receptor (AHR). |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.5224 mL | 12.6119 mL | 25.2239 mL | 50.4477 mL |
| 5mM | 0.5045 mL | 2.5224 mL | 5.0448 mL | 10.0895 mL |
| 10mM | 0.2522 mL | 1.2612 mL | 2.5224 mL | 5.0448 mL |
| 20mM | 0.1261 mL | 0.6306 mL | 1.2612 mL | 2.5224 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start)
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Volume(start)
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Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
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Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.