PIK-93

This product is for research use only, not for human use. We do not sell to patients.

PIK-93
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$925Check With Us
500mg$1420Check With Us
1g$2130Check With Us

Cat #: V0120 CAS #: 593960-11-3 Purity ≥ 98%

Description: PIK-93, a phenylthiazole analog, is a novel, potent, and selective PI4K (PI4KIIIβ) inhibitor with antiviral effects (antienterovirus activity).

References: Knight ZA, et al. A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling. Cell. 2006 May 19;125(4):733-47

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Product Promise

Promise
Molecular Weight (MW)389.88
Molecular FormulaC14H16ClN3O4S2
CAS No.593960-11-3
Solubility In VitroDMSO: 78 mg/mL (200.1 mM)r
Water:<1 mg/mLr
Ethanol: <1 mg/mL
Solubility In Vivo30% PEG400+0.5% Tween80+5% Propylene glycol: 30 mg/mL
SMILES CodeCC(NC1=NC(C)=C(C2=CC=C(Cl)C(S(=O)(NCCO)=O)=C2)S1)=O
SynonymsPIK93; PIK 93; PIK-93
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.5649 mL12.8245 mL25.6489 mL51.2978 mL
5mM0.5130 mL2.5649 mL5.1298 mL10.2596 mL
10mM0.2565 mL1.2824 mL2.5649 mL5.1298 mL
20mM0.1282 mL0.6412 mL1.2824 mL2.5649 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.