Tenalisib R Enantiomer
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $1800 | Check With Us |
| 250mg | $2980 | Check With Us |
| 500mg | $4470 | Check With Us |
: Cat #: V3108 CAS #: 1639417-54-1 Purity ≥ 98%
Description: Tenalisib R Enantiomer is the R-isomer of Tenalisib (also known as RP-6530).
Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products
Product Promise
- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 415.42 |
|---|---|
| Molecular Formula | C23H18FN5O2 |
| CAS No. | 1639417-54-1 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 10 mMr |
| Water: N/Ar | |
| Ethanol: N/A | |
| SMILES Code | O=C1C(C2=CC=CC(F)=C2)=C([C@@H](NC3=C4NC=NC4=NC=N3)CC)OC5=CC=CC=C15 |
| Synonyms | RP6530 R Enantiomer ; RP-6530 R Enantiomer ; RP 6530 R Enantiomer |
| Protocol | In Vitro | Tenalisib, a dual PI3K δ/γ inhibitor, potentiates Ruxolitinib activity in the JAK2-V617F mutant erythroleukemia cell lines. |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.4072 mL | 12.0360 mL | 24.0720 mL | 48.1440 mL |
| 5mM | 0.4814 mL | 2.4072 mL | 4.8144 mL | 9.6288 mL |
| 10mM | 0.2407 mL | 1.2036 mL | 2.4072 mL | 4.8144 mL |
| 20mM | 0.1204 mL | 0.6018 mL | 1.2036 mL | 2.4072 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.