Clinofibrate
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 500mg | $900 | Check With Us |
| 1g | $1350 | Check With Us |
| 5g | $3415 | Check With Us |
: Cat #: V0930 CAS #: 30299-08-2 Purity ≥ 98%
Description: Clinofibrate (Lipoclin; S-8527; S 8527) is a potent anti-hyperlipidemic agent which acts as an HMG-CoA (hydroxymethylglutaryl coenzyme A) reductase inhibitor with potential anti-hyperlipidemic effects.
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- Physicochemical and Storage Information
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- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 468.58 |
|---|---|
| Molecular Formula | C28H36O6 |
| CAS No. | 30299-08-2 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 94 mg/mL (200.6 mM)r |
| Water:<1 mg/mLr | |
| Ethanol: 94 mg/mL (200.6 mM) | |
| SMILES Code | CCC(C)(OC1=CC=C(C2(C3=CC=C(OC(CC)(C(O)=O)C)C=C3)CCCCC2)C=C1)C(O)=O |
| Synonyms | S8527; Lipoclin; Clinofibrate; S-8527; S 8527 |
| Protocol | In Vitro | Clinofibrate administration (50 and 100 mg/kg/day, p.o.) significantly inhibits the increase in plasma fibrinogen level as well as serum- and VLDL-LDL-lipid. |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.1341 mL | 10.6705 mL | 21.3411 mL | 42.6821 mL |
| 5mM | 0.4268 mL | 2.1341 mL | 4.2682 mL | 8.5364 mL |
| 10mM | 0.2134 mL | 1.0671 mL | 2.1341 mL | 4.2682 mL |
| 20mM | 0.1067 mL | 0.5335 mL | 1.0671 mL | 2.1341 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.