Rosuvastatin D6 Calcium | CAS N/A (Rosuvastatin D6 Calcium); N/A ( Rosuvastatin D6 Sodium); 1279031-70-7 (Rosuvastatin D3 Sodium); 287714-41-4 (Rosuvastatin); 147098-20-2 (Rosuvastatin calcium)

Rosuvastatin D6 Calcium

This product is for research use only, not for human use. We do not sell to patients.

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Size	Price	Stock
100mg	$3570	Check With Us
200mg	$5355	Check With Us
500mg	$9035	Check With Us

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Cat #: V3297 CAS #: N/A (Rosuvastatin D6 Calcium); N/A ( Rosuvastatin D6 Sodium); 1279031-70-7 (Rosuvastatin D3 Sodium); 287714-41-4 (Rosuvastatin); 147098-20-2 (Rosuvastatin calcium) Purity ≥ 98%

Description: Rosuvastatin D6 Calcium is deuterium labeled Rosuvastatin Calcium (also known as S-4522, Rosuvastatin hemicalcium; ZD 4522 Calcium and ZD 4522, trade name: Crestor) which is a member of the statin class of drugs and a competitive inhibitor of HMG-CoA reductase with IC50 of 11 nM in a cell-free assay.

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Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	506.61
Molecular Formula	C₂₂H₂₁D₆FN₃O₆S . ₁/₂ Ca
CAS No.	N/A (Rosuvastatin D6 Calcium); N/A ( Rosuvastatin D6 Sodium); 1279031-70-7 (Rosuvastatin D3 Sodium); 287714-41-4 (Rosuvastatin); 147098-20-2 (Rosuvastatin calcium)
Storage	-20℃ for 3 years in powder formr
Storage	-80℃ for 2 years in solvent
Solubility In Vitro	DMSO: 10mM)r
	Water:r
	Ethanol:
Solubility In Vivo	4% DMSO+30% PEG 300+dd H2O: 10 mg/mL
SMILES Code	O=C([O-])C[C@H](O)C[C@H](O)/C=C/C1=C(C(C([2H])([2H])[2H])C([2H])([2H])[2H])N=C(N(C)S(=O)(C)=O)N=C1C2=CC=C(F)C=C2.[0.5Ca2+]
Synonyms	Rosuvastatin calcium (ZD 4522; ZD-4522; ZD4522; S-4522; S 4522; S4522; ZD 4522 calcium salt; Rosuvastatin calcium; Brand name: Crestor.)

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	1.9739 mL	9.8695 mL	19.7390 mL	39.4781 mL
5mM	0.3948 mL	1.9739 mL	3.9478 mL	7.8956 mL
10mM	0.1974 mL	0.9870 mL	1.9739 mL	3.9478 mL
20mM	0.0987 mL	0.4935 mL	0.9870 mL	1.9739 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.