Trilostane | CAS 13647-35-3

Trilostane

This product is for research use only, not for human use. We do not sell to patients.

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Size	Price	Stock
2g	$600	Check With Us
5g	$1050	Check With Us
10g	$1575	Check With Us

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Cat #: V0860 CAS #: 13647-35-3 Purity ≥ 98%

Description: Trilostane (also known as WIN 24540; Desopan; DB-011080; Win-24540; Modrastane) is a potent inhibitor of 3β-hydroxysteroid dehydrogenase that was used in the treatment of Cushing's syndrome, Conn's syndrome, and postmenopausal breast cancer in humans.

References: JA Braddock, et al. Trilostane treatment in dogs with pituitary-dependent hyperadreno-corticism. Veterinary Journal. 10 March 2008.

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Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	329.43
Molecular Formula	C20H27NO3
CAS No.	13647-35-3
Storage	-20℃ for 3 years in powder formr
Storage	-80℃ for 2 years in solvent
Solubility In Vitro	DMSO: 65 mg/mL (197.3 mM)r
	Water: <1 mg/mLr
	Ethanol: <1 mg/mL
SMILES Code	N#CC1=C(O)[C@@]2([H])O[C@@]23[C@]([C@@]4([H])CC[C@@]5(C)[C@](CC[C@@H]5O)([H])[C@]4([H])CC3)(C)C1
Synonyms	WIN 24540; WIN24540; Trilostane; D 01180; Modrastane. Desopan; DB011080; WIN-24540; D-01180; Modrenal.

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	3.0355 mL	15.1777 mL	30.3555 mL	60.7109 mL
5mM	0.6071 mL	3.0355 mL	6.0711 mL	12.1422 mL
10mM	0.3036 mL	1.5178 mL	3.0355 mL	6.0711 mL
20mM	0.1518 mL	0.7589 mL	1.5178 mL	3.0355 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.