Clofibric Acid

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
50g	$400	Check With Us
100g	$600	Check With Us
200g	$900	Check With Us

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Cat #: V0837 CAS #: 882-09-7 Purity ≥ 99%

Description: Clofibric acid (BRN-1874067; CCRIS 9254; BRN1874067; NSC 1149; NSC1149; Chlorofibrinic acid), the active metabolite of clofibrate, etofibrate and theofibrate (the lipid-lowering drugs), is a potent PPARα agonist and anti-hyperlipidemic agent.

References: Forman BM, et, al. Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta. Proc Natl Acad Sci U S A. 1997 Apr 29;94(9):4312-7.

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Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	214.65
Molecular Formula	C10H11ClO3
CAS No.	882-09-7
Storage	-20℃ for 3 years in powder formr
Storage	-80℃ for 2 years in solvent
Solubility In Vitro	DMSO: 43 mg/mL (200.3 mM)r
	Water: <1 mg/mLr
	Ethanol: 43 mg/mL (200.3 mM)
SMILES Code	CC(C)(OC1=CC=C(Cl)C=C1)C(O)=O
Synonyms	BRN-1874067; CCRIS 9254; BRN1874067; NSC 1149; NSC1149; NSC-1149; BRN 1874067; CCRIS-9254; CCRIS9254 Chlorfibrinic acid;

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	4.6587 mL	23.2937 mL	46.5875 mL	93.1749 mL
5mM	0.9317 mL	4.6587 mL	9.3175 mL	18.6350 mL
10mM	0.4659 mL	2.3294 mL	4.6587 mL	9.3175 mL
20mM	0.2329 mL	1.1647 mL	2.3294 mL	4.6587 mL

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.