Pemafibrate [(R)-K-13675]

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
250mg	$1250	In Stock
500mg	$2050	In Stock
1g	$3075	In Stock

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Cat #: V17606 CAS #: 848259-27-8 Purity ≥ 98%

Description: Pemafibrate [(R)-K 13675; K877; Parmodia], a drug used for the reduction of triglycerides, is a potent agonist of peroxisome proliferator-activated receptor alpha (PPAR alpha/PPARα) with EC50 of 1 nM.

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Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	490.56
Molecular Formula	C28H30N2O6
CAS No.	848259-27-8
SMILES Code	CC[C@@H](OC1=CC=CC(CN(C2=NC3=CC=CC=C3O2)CCCOC4=CC=C(OC)C=C4)=C1)C(O)=O
Synonyms	K877; (R)-K13675; K-877; (R)-K 13675; K 877; (R) K-13675; Pemafibrate sodium; (R)-K 13675; Parmodia

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	2.0385 mL	10.1924 mL	20.3849 mL	40.7697 mL
5mM	0.4077 mL	2.0385 mL	4.0770 mL	8.1539 mL
10mM	0.2038 mL	1.0192 mL	2.0385 mL	4.0770 mL
20mM	0.1019 mL	0.5096 mL	1.0192 mL	2.0385 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.