GW6471

This product is for research use only, not for human use. We do not sell to patients.

GW6471
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$950Check With Us
250mg$1700Check With Us
500mg$2550Check With Us

Cat #: V4916 CAS #: 880635-03-0 Purity ≥ 98%

Description: GW 6471 (GW6471; GW-6471) is a novel and potent PPARα antagonistwith an IC50 of 0.24 μ M.

References: Xu HE, et al. Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARalpha. Nature. 2002 Feb 14;415(6873):813-7.

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Product Promise

Promise
Molecular Weight (MW)619.67
Molecular FormulaC35H36F3N3O4
CAS No.880635-03-0
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
SMILES CodeCCC(NC[C@@H](N/C(C)=C\C(C1=CC=C(C(F)(F)F)C=C1)=O)CC2=CC=C(OCCC3=C(C)OC(C4=CC=CC=C4)=N3)C=C2)=O
SynonymsGW6471; GW-6471; GW 6471
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.6138 mL8.0688 mL16.1376 mL32.2752 mL
5mM0.3228 mL1.6138 mL3.2275 mL6.4550 mL
10mM0.1614 mL0.8069 mL1.6138 mL3.2275 mL
20mM0.0807 mL0.4034 mL0.8069 mL1.6138 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.