Diosgenin

This product is for research use only, not for human use. We do not sell to patients.

Diosgenin
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
10g$250Check With Us
50g$700Check With Us
100g$1050Check With Us

Cat #: V1999 CAS #: 512-04-9 Purity ≥ 98%

Description: Diosgenin is a plant steroidal sapogenin which induces apoptosis in colon cancer cell lines and induces apoptosis,cell cycle arrest and COX activity in osteosarcoma cells.

References: Li F, et al. Diosgenin, a steroidal saponin, inhibits STAT3 signaling pathway leading to suppression of proliferation and chemosensitization of human hepatocellular carcinoma cells. Cancer Lett. 2010 Jun 28;292(2):197-207.

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Product Promise

Promise
Molecular Weight (MW)414.62
Molecular FormulaC27H42O3
CAS No.512-04-9
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: <1 mg/mLr
Water: <1 mg/mLr
Ethanol: 83 mg/mL (200.2 mM)
SMILES Code[H][C@]1(O[C@@]2(OCC(C)CC2)[C@H]3C)C[C@@]4([H])[C@]5([H])CC=C6CC(O)CC[C@]6(C)[C@@]5([H])CC[C@]4(C)[C@]13[H]
Synonyms(3β,25R)-spirost-5-en-3-ol
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.4118 mL12.0592 mL24.1185 mL48.2369 mL
5mM0.4824 mL2.4118 mL4.8237 mL9.6474 mL
10mM0.2412 mL1.2059 mL2.4118 mL4.8237 mL
20mM0.1206 mL0.6030 mL1.2059 mL2.4118 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.