Home > Signaling Pathways>Anti-infection>HIV>Ro 24-7429
Ro 24-7429

This product is for research use only, not for human use. We do not sell to patients.

Ro 24-7429
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$1715To Be Confirmed
200mg$2570To Be Confirmed
500mg$4340To Be Confirmed
email: [email protected]        [email protected]

Cat #: V8379 CAS #: 139339-45-0 Purity ≥ 99%

Description: Ro 24-7429 (Ro247429; Ro-247429) is a novel and potent Tat ( HIV-1 transactivator protein) antagonist with anti-HIV, antifibrotic and anti-inflammatory activities.

References: A H Patki, et al. HIV-1 Tat protein and its inhibitor Ro 24-7429 inhibit lymphocyte proliferation and induce apoptosis in peripheral blood mononuclear cells from healthy donors. Cell Immunol. 1996 Apr 10;169(1):40-6.

Top Publications Citing Invivochem Products
Product Catalog 2022
Bulletin Board
Guide to Product Handling
Publications Citing InvivoChem Products
Product Promise
Promise
Molecular Weight (MW)272.73
Molecular FormulaC14H13ClN4
CAS No.139339-45-0
SMILES CodeCNC1=NC2=CC=C(Cl)C=C2C(C3=CC=CN3
Synonyms Ro247429; Ro-247429; Ro 247429; Ro 24-7429; Ro-24-7429; Ro247429;
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.6666 mL18.3332 mL36.6663 mL73.3326 mL
5mM0.7333 mL3.6666 mL7.3333 mL14.6665 mL
10mM0.3667 mL1.8333 mL3.6666 mL7.3333 mL
20mM0.1833 mL0.9167 mL1.8333 mL3.6666 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
 
=
Concentration
 
×
Volume
 
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
 
×
 
Volume(start)
V1
 
=
 
Concentration(final)
C2
 
×
 
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.