Fostemsavir Tris (BMS-663068 trisaminomethane)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
Size | Price | Stock |
---|---|---|
100mg | $1250 | Check With Us |
250mg | $1850 | Check With Us |
500mg | $2775 | Check With Us |
Cat #: V29032 CAS #: 864953-39-9 Purity ≥ 99%
Description: Fostemsavir Tris (BMS-663068 trisaminomethane or tromethamine or THAM) is the trisaminomethane salt of Fostemsavir (BMS663068; BMS-663068; Rukobia) which is an anti-HIV medication marketed in 2020.
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Molecular Weight (MW) | 704.62 |
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Molecular Formula | C₂₉H₃₇N₈O₁₁P |
CAS No. | 864953-39-9 |
SMILES Code | O=C(N1CCN(C(C2=CC=CC=C2)=O)CC1)C(C3=CN(COP(O)(O)=O)C4=C3C(OC)=CN=C4N5N=C(C)N=C5)=O.OCC(CO)(N)CO |
Synonyms | BMS-663068 dihydrate; BMS 663068; MS-663068 Tris; BMS-663068; BMS663068; |
Protocol | In Vitro | Fostemsavir Tris has good antiviral activity in subjects infected with virus shown to be susceptible (IC50, <100 nM) to the agent. |
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These protocols are for reference only. InvivoChem does not
independently validate these methods.
Solvent volume to be added | Mass (the weight of a compound) | |||
---|---|---|---|---|
Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
1mM | 1.4192 mL | 7.0960 mL | 14.1920 mL | 28.3841 mL |
5mM | 0.2838 mL | 1.4192 mL | 2.8384 mL | 5.6768 mL |
10mM | 0.1419 mL | 0.7096 mL | 1.4192 mL | 2.8384 mL |
20mM | 0.0710 mL | 0.3548 mL | 0.7096 mL | 1.4192 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Concentration
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Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
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Volume(start)
=
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Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
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Volume(start)
V1
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Concentration(final)
C2
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V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.