Bayer 41-4109 S-enantiomer
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $2150 | To Be Confirmed |
| 250mg | $3350 | To Be Confirmed |
| 500mg | $5025 | To Be Confirmed |
: Cat #: V4199 CAS #: 476617-51-3 Purity ≥ 98%
Description: Bay 41-4109 S-isomer is the less active enantiomer of Bay 41-4109.
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| Molecular Weight (MW) | 395.76 |
|---|---|
| Molecular Formula | C18H13ClF3N3O2 |
| CAS No. | 476617-51-3 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| SMILES Code | O=C(C1=C(C)NC(C2=NC=C(F)C=C2F)=NC1C3=CC=C(F)C=C3Cl)OC |
| Synonyms | BAY-41-4109; BAY41-4109; BAY 41-4109; BAY-414109 S-isomer; BAY414109 S-isomer; BAY 414109; |
| Protocol | In Vitro | BAY 41-4109 is able to both accelerate and misdirect capsid assembly in vitro. Preformed capsids are stabilized by BAY 41-4109, up to a ratio of one inhibitor molecule per two dimers. |
|---|---|---|
| In Vivo | BAY 41-4109 reduces viral DNA in the liver and in the plasma dose-dependently with efficacy comparable to 3TC. BAY 41 -4109 reduces hepatitis B virus core antigen (HBcAg) in livers of HBV-transgenic mice. Pharmacokinetic studies in mice have shown rapid absorption, a bioavailability of 30% and dose-proportional plasma concentrations, about 60% in rats and dogs. |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.5268 mL | 12.6339 mL | 25.2678 mL | 50.5357 mL |
| 5mM | 0.5054 mL | 2.5268 mL | 5.0536 mL | 10.1071 mL |
| 10mM | 0.2527 mL | 1.2634 mL | 2.5268 mL | 5.0536 mL |
| 20mM | 0.1263 mL | 0.6317 mL | 1.2634 mL | 2.5268 mL |
The molarity calculator equation
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The dilution calculator equation
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This equation is commonly abbreviated as: C1 V1 = C2 V2
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Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
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mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.