ZM223

This product is for research use only, not for human use. We do not sell to patients.

ZM223
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$2350Check With Us
200mg$3525Check With Us
500mg$5950Check With Us

Cat #: V31900 CAS #: 2031177-48-5 Purity ≥ 99%

Description: ZM223 is a potent non-covalent NEDD8 activating enzyme (NAE) inhibitor, orally bioavailable.

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Product Promise

Promise
Molecular Weight (MW)502.5302
Molecular FormulaC23H17F3N4O2S2
CAS No.2031177-48-5
SMILES CodeO=C(C1=CC=C(C(F)(F)F)C=C1)NC2=NC3=CC=C(NC(CSC4=CC=C(N)C=C4)=O)C=C3S2
SynonymsZM223; ZM 223; ZM-223
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.9899 mL9.9497 mL19.8993 mL39.7986 mL
5mM0.3980 mL1.9899 mL3.9799 mL7.9597 mL
10mM0.1990 mL0.9950 mL1.9899 mL3.9799 mL
20mM0.0995 mL0.4975 mL0.9950 mL1.9899 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.