PTP1B-IN-1
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $1530 | Check With Us |
| 250mg | $2290 | Check With Us |
| 500mg | $3435 | Check With Us |
: Cat #: V2859 CAS #: 612530-44-6 Purity ≥ 98%
Description: PTP1B-IN-1 is a potent and new class of inhibitor of protein tyrosine phosphatase-1B (PTP1B) with IC50 of 1.6 mM; It incorporates the 1,2,5-thiadiazolidin-3-one-1,1-dioxide template that was identified through structure-based design.
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- Physicochemical and Storage Information
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| Molecular Weight (MW) | 212.23 |
|---|---|
| Molecular Formula | C₈H₈N₂O₃S |
| CAS No. | 612530-44-6 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: ≥ 38 mg/mLr |
| Water: <1 mg/mLr | |
| Ethanol: | |
| SMILES Code | O=C(CN1C2=CC=CC=C2)NS1(=O)=O |
| Synonyms | PTP1B inhibitor 1; PTP1B-inhibitor-1; PTP1B-IN-1; PTP1B IN 1; PTP1BIN1 |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 4.7119 mL | 23.5593 mL | 47.1187 mL | 94.2374 mL |
| 5mM | 0.9424 mL | 4.7119 mL | 9.4237 mL | 18.8475 mL |
| 10mM | 0.4712 mL | 2.3559 mL | 4.7119 mL | 9.4237 mL |
| 20mM | 0.2356 mL | 1.1780 mL | 2.3559 mL | 4.7119 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.