NSC-663284

This product is for research use only, not for human use. We do not sell to patients.

NSC-663284
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$1340Check With Us
500mg$1950Check With Us
1g$2925Check With Us

Cat #: V4755 CAS #: 383907-43-5 Purity ≥ 98%

Description: NSC-663284 (also known as SPS-8I1; DA3003-1) is a novel and potent inhibitor of the Cdc25 dual specificity phosphatases and SETD8 with anticancer activity.

References: Lazo JS, et al. Discovery and biological evaluation of a new family of potent inhibitors of the dual specificity protein phosphatase Cdc25. J Med Chem. 2001 Nov 22;44(24):4042-9.

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Product Promise

Promise
Molecular Weight (MW)321.76
Molecular FormulaC15H16ClN3O3
CAS No.383907-43-5
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
SMILES CodeO=C(C(Cl)=C1NCCN2CCOCC2)C3=C(N=CC=C3)C1=O
SynonymsSPS8I1; SPS-8I1; SPS 8I1; DA3003-1; DA3003 1; DA30031; NSC-663284; NSC 663284; NSC663284;
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.1079 mL15.5395 mL31.0791 mL62.1581 mL
5mM0.6216 mL3.1079 mL6.2158 mL12.4316 mL
10mM0.3108 mL1.5540 mL3.1079 mL6.2158 mL
20mM0.1554 mL0.7770 mL1.5540 mL3.1079 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.