SURAMIN SODIUM

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
500mg	$980	Check With Us
1g	$1450	Check With Us
5g	$3670	Check With Us

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Cat #: V4335 CAS #: 129-46-4 Purity ≥ 98%

Description: Suramin sodium salt, a polysulfonated naphthylurea analog, is a novel and potent DNA topoisomerase II inhibitor with an IC50 of 5 μM.

References: Zhang YL, et al. Suramin is an active site-directed, reversible, and tight-binding inhibitor of protein-tyrosine phosphatases. J Biol Chem. 1998 May 15;273(20):12281-7.

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Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	1429.17
Molecular Formula	C51H34N6Na6O23S6
CAS No.	129-46-4
Storage	-20℃ for 3 years in powder formr
Storage	-80℃ for 2 years in solvent
SMILES Code	O=C(NC1=CC(C(NC2=CC(C(NC(C(C3=CC(S([O-])(=O)=O)=C4)=C4S([O-])(=O)=O)=CC=C3S([O-])(=O)=O)=O)=CC=C2C)=O)=CC=C1)NC5=CC(C(NC6=CC(C(NC7=CC=C(S(=O)([O-])=O)C8=CC(S(=O)([O-])=O)=CC(S(=O)([O-])=O)=C78)=O)=CC=C6C)=O)=CC=C5.[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]
Synonyms	NSC-34936l; NSC34936 ; NSC 34936;Suramin Hexasodium; BAY 205; BAY-205; BAY205; Germanin; NF 060; NF-060; NF060; Suramin; Farma; Fourneau;

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	0.6997 mL	3.4985 mL	6.9971 mL	13.9941 mL
5mM	0.1399 mL	0.6997 mL	1.3994 mL	2.7988 mL
10mM	0.0700 mL	0.3499 mL	0.6997 mL	1.3994 mL
20mM	0.0350 mL	0.1749 mL	0.3499 mL	0.6997 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.

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