ent-Ezetimibe

This product is for research use only, not for human use. We do not sell to patients.

ent-Ezetimibe
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$1350To Be Confirmed
200mg$2025To Be Confirmed
500mg$3415To Be Confirmed

Cat #: V40059 CAS #: 1376614-99-1 Purity ≥ 99%

Description: ent-Ezetimibe is the RRS-enantiomer and impurity of Ezetimibe (SCH-58235), which is a selective inhibitor of cholesterol absorption in the gut used to lower cholesterol levels.

References: Lee DH, et al. Ezetimibe, an NPC1L1 inhibitor, is a potent Nrf2 activator that protects mice from diet-induced nonalcoholic steatohepatitis. Free Radic Biol Med. 2016 Sep 12;99:520-532.

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Molecular Weight (MW)409.43
Molecular FormulaC24H21F2NO3
CAS No.1376614-99-1
SynonymsentEzetimibe; ent Ezetimibe
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.4424 mL12.2121 mL24.4242 mL48.8484 mL
5mM0.4885 mL2.4424 mL4.8848 mL9.7697 mL
10mM0.2442 mL1.2212 mL2.4424 mL4.8848 mL
20mM0.1221 mL0.6106 mL1.2212 mL2.4424 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.