meta-Fexofenadine (meta-MDL-16455

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
100mg	$1875	To Be Confirmed
200mg	$2810	To Be Confirmed
500mg	$4740	To Be Confirmed

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Cat #: V32648 CAS #: 479035-75-1 Purity ≥ 99%

Description: meta-Fexofenadine (meta-MDL-1645; meta-MDL16455) is an impurity of Fexofenadine (Allegra; MDL-16455A; MDL16455A; Telfast), which is a histamine H1 receptor antagonist (antihistamine) approved for the treatment of allergy including hay fever, nasal congestion, and urticaria.

References: Maher HM, et al. Development of validated stability-indicating chromatographic method for the determination of fexofenadine hydrochloride and its related impurities in pharmaceutical tablets. Chem Cent J. 2011 Dec 3;5(1):76.

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Molecular Weight (MW)	501.66
Molecular Formula	C32H39NO4
CAS No.	479035-75-1
Synonyms	meta-MDL-16455; meta-Terfenadine carboxylate

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	1.9934 mL	9.9669 mL	19.9338 mL	39.8676 mL
5mM	0.3987 mL	1.9934 mL	3.9868 mL	7.9735 mL
10mM	0.1993 mL	0.9967 mL	1.9934 mL	3.9868 mL
20mM	0.0997 mL	0.4983 mL	0.9967 mL	1.9934 mL

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.