Dihydro Dutasteride

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
100mg	$1599	To Be Confirmed
200mg	$2400	To Be Confirmed
500mg	$4050	To Be Confirmed

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Cat #: V40044 CAS #: 164656-22-8 Purity ≥ 99%

Description: Dihydro Dutasteride is an impurity generated during the production of Dutasteride (GI198745, GG745; GI-198745, GG-745; Avodart, Avidart), which is an approved anticancer medication and a 5-α reductase inhibitor.

References: Lazier CB, et al. Dutasteride, the dual 5alpha-reductase inhibitor, inhibits androgen action and promotes cell death in the LNCaP prostate cancer cell line. Prostate. 2004 Feb 1;58(2):130-44.

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Molecular Weight (MW)	530.55
Molecular Formula	C27H32F6N2O2
CAS No.	164656-22-8
SMILES Code	O=C([C@H]1CC[C@]2([H])[C@]1(C)CC[C@]3([H])[C@@]4(C)CCC(N[C@]4([H])CC[C@]32[H])=O)NC5=CC(C(F)(F)F)=CC=C5C(F)(F)F
Synonyms	Dihydrodutasteride

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	1.8848 mL	9.4242 mL	18.8484 mL	37.6967 mL
5mM	0.3770 mL	1.8848 mL	3.7697 mL	7.5393 mL
10mM	0.1885 mL	0.9424 mL	1.8848 mL	3.7697 mL
20mM	0.0942 mL	0.4712 mL	0.9424 mL	1.8848 mL

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.