4-Hydroxyquinoline
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 10g | $350 | Check With Us |
| 25g | $650 | Check With Us |
| 50g | $975 | Check With Us |
: Cat #: V9595 CAS #: 611-36-9 Purity ≥ 98%
Description: 4-Hydroxyquinoline is a quinolone compound which forms the core moiety of antibacterials.
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| Molecular Weight (MW) | 145.16 |
|---|---|
| Molecular Formula | C9H7NO |
| CAS No. | 611-36-9 |
| SMILES Code | OC1=CC=NC2=CC=CC=C12 |
| Synonyms | 4-Hydroxyquinoline; 4Hydroxyquinoline; Kynurine; 4 Hydroxyquinoline; |
| Protocol | In Vitro | 4-Quinolone (Kynurine) promotes tumor cell survival and motility by suppressing antitumor immune responses through AhR in an autocrine/paracrine fashion. This system is particularly active in human brain tumors where the activation of AhR enhances the expression of TDO producing more kynurine and kynurinic acid. In the healthy human brain, very low levels of TDO exist, whereas, in human brain tumors, the TDO protein levels increase with malignancy. |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 6.8890 mL | 34.4448 mL | 68.8895 mL | 137.7790 mL |
| 5mM | 1.3778 mL | 6.8890 mL | 13.7779 mL | 27.5558 mL |
| 10mM | 0.6889 mL | 3.4445 mL | 6.8890 mL | 13.7779 mL |
| 20mM | 0.3444 mL | 1.7222 mL | 3.4445 mL | 6.8890 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
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Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
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Concentration(final)
C2
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Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.