Glycine (AZD4282)

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
5g	$120	Check With Us
10g	$200	Check With Us
20g	$300	Check With Us

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Cat #: V8359 CAS #: 56-40-6 Purity ≥ 99%

Description: Glycine (AZD-4282, aminoacetic acid), one of the 20 essential amino acids to make proteins in human body, is an inhibitory neurotransmitter which acts as a N-methyl-D-aspartate (NMDA) receptor antagonist and has the potential for the treatment of neuropathic pain.

References: Johnson JW, et al. Glycine potentiates the NMDA response in cultured mouse brain neurons. Nature. 1987 Feb 5-11;325(6104):529-31.

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Molecular Weight (MW)	75.07
Molecular Formula	C2H5NO2
CAS No.	56-40-6
Synonyms	Glycine

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	13.3209 mL	66.6045 mL	133.2090 mL	266.4180 mL
5mM	2.6642 mL	13.3209 mL	26.6418 mL	53.2836 mL
10mM	1.3321 mL	6.6605 mL	13.3209 mL	26.6418 mL
20mM	0.6660 mL	3.3302 mL	6.6605 mL	13.3209 mL

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.