L-Cystathionine

This product is for research use only, not for human use. We do not sell to patients.

L-Cystathionine
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$550To Be Confirmed
250mg$1050To Be Confirmed
500mg$1575To Be Confirmed

Cat #: V18189 CAS #: 56-88-2 Purity ≥ 99%

Description: L-Cystathionine is a non-protein and sulfur-containing amino acid associated with the metabolism of sulfur-containing amino acids.

References: Xiuli Wang, et al. L-Cystathionine Protects against Homocysteine-Induced Mitochondria-Dependent Apoptosis of Vascular Endothelial Cells. Oxid Med Cell Longev. 2019 Nov 25;2019:1253289.

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Molecular Weight (MW)222.26
Molecular FormulaC7H14N2O4S
CAS No.56-88-2
SMILES CodeO=C(O)[C@H](N)CCSC[C@@H](N)C(O)=O
SynonymsL-Cystathionine; L-(+)-Cystathionine; Cystathionine, L
ProtocolIn VitroHomocysteine obviously induces the apoptosis of HUVECs, and this effect is significantly attenuated by the pretreatment with L-cystathionine. Furthermore, L-cystathionine decreases the production of mitochondrial superoxide anion and the expression of Bax and restrained its translocation to mitochondria, increases mitochondrial membrane potential, inhibits mitochondrial permeability transition pore (MPTP) opening, suppresses the leakage of cytochrome c from mitochondria into the cytoplasm, and downregulated activities of caspase-9 and caspase-3.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM4.4992 mL22.4962 mL44.9924 mL89.9847 mL
5mM0.8998 mL4.4992 mL8.9985 mL17.9969 mL
10mM0.4499 mL2.2496 mL4.4992 mL8.9985 mL
20mM0.2250 mL1.1248 mL2.2496 mL4.4992 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
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Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.