Prostaglandin E2 (Dinoprostone)

This product is for research use only, not for human use. We do not sell to patients.

Prostaglandin E2 (Dinoprostone)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$750In Stock
500mg$1200In Stock
1g$1800In Stock

Cat #: V5221 CAS #: 363-24-6 Purity ≥ 98%

Description: Prostaglandin E2 (PGE2; dinoprostone) is a naturally occurring prostaglandin which is used as a medication in labor induction, bleeding after delivery, termination of pregnancy, and in newborn babies to keep the ductus arteriosus open.

References: Chouaib S, et al. The mechanisms of inhibition of human IL 2 production. II. PGE2 induction of suppressor T lymphocytes. J Immunol. 1984 Apr;132(4):1851-7.

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Product Promise

Promise
Molecular Weight (MW)352.47
Molecular FormulaC20H32O5
CAS No.363-24-6
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
SMILES CodeO[C@@H]1CC([C@H](C/C=C\CCCC(O)=O)[C@H]1/C=C/[C@@H](O)CCCCC)=O
SynonymsU 12062; U12062; U-12062; PGE2; Prostaglandin E2; Dinoprostone;
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.8371 mL14.1856 mL28.3712 mL56.7424 mL
5mM0.5674 mL2.8371 mL5.6742 mL11.3485 mL
10mM0.2837 mL1.4186 mL2.8371 mL5.6742 mL
20mM0.1419 mL0.7093 mL1.4186 mL2.8371 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.