GW-7647

This product is for research use only, not for human use. We do not sell to patients.

GW-7647
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$1020To Be Confirmed.
500mg$1480To Be Confirmed.
1g$2220To Be Confirmed.

Cat #: V4928 CAS #: 265129-71-3 Purity ≥ 98%

Description: GW7647 (GW-7647) is a novel, selective and potent agonist of human and murine PPARα4 with EC50s of 6 nM, 1.1 μM, and 6.2 μM for human PPARα, PPARγ and PPARδ, respectively.

References: Lam VH, et al. Activating PPARα prevents post-ischemic contractile dysfunction in hypertrophied neonatal hearts. Circ Res. 2015 Jun 19;117(1):41-51.

Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products

Product Promise

Promise
Molecular Weight (MW)502.75
Molecular FormulaC29H46N2O3S
CAS No.265129-71-3
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
ProtocolIn VivoGW7647 (3 mg/kg per day) does not prevent the development of cardiac hypertrophy, but it prevents the decline in left ventricular ejection fraction in vivo
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.9891 mL9.9453 mL19.8906 mL39.7812 mL
5mM0.3978 mL1.9891 mL3.9781 mL7.9562 mL
10mM0.1989 mL0.9945 mL1.9891 mL3.9781 mL
20mM0.0995 mL0.4973 mL0.9945 mL1.9891 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.