Choline Fenofibrate
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 250mg | $1150 | Check With Us |
| 500mg | $1850 | Check With Us |
| 1g | $2775 | Check With Us |
: Cat #: V4093 CAS #: 856676-23-8 Purity ≥ 98%
Description: Choline fenofibrate (formerly also known as ABT-335 or choline salt of fenofibric acid) is a novel, synthetic phenoxy-isobutyric acid derivate with antihyperlipidemic activity that acts as an PPARα agonist.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 421.92 |
|---|---|
| Molecular Formula | C22H28ClNO5 |
| CAS No. | 856676-23-8 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 5 mg/mLr |
| Water: 9 mg/mLr | |
| Ethanol: 7 mg/mL | |
| SMILES Code | OCC[N+](C)(C)C.CC(C)(OC1=CC=CC=C1C(C2=CC=C(Cl)C=C2)=O)C([O-])=O |
| Synonyms | ABT-335; ABT 335; ABT335; Choline fenofibrate; HIP0901; HIP-0901; HIP 0901; Trilipix. Fibricor; fenofibric acid |
| Protocol | In Vivo | Choline Fenofibrate exhibits excellent absolute oral bioavailability (rat 93.4%) and Cmax (rat 7944.2 ng/mL) following oral administration (rat 4mg/kg) |
|---|---|---|
| Animal model | Male Sprague-Dawley (SD) rats (200-250g) | |
| Dosages | 4 mg/kg (Pharmacokinetic Analysis) | |
| Administration | Intravenous injection and oral administration |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.3701 mL | 11.8506 mL | 23.7012 mL | 47.4024 mL |
| 5mM | 0.4740 mL | 2.3701 mL | 4.7402 mL | 9.4805 mL |
| 10mM | 0.2370 mL | 1.1851 mL | 2.3701 mL | 4.7402 mL |
| 20mM | 0.1185 mL | 0.5925 mL | 1.1851 mL | 2.3701 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.