Tubulin inhibitor 6

This product is for research use only, not for human use. We do not sell to patients.

Tubulin inhibitor 6
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$650Check With Us
250mg$1100Check With Us
500mg$1650Check With Us

Cat #: V39080 CAS #: 105925-39-1 Purity ≥ 99%

Description: Tubulin inhibitor 6 (Compound 14b) is a novel and potent tubulin inhibitor (mitotic inhibitor or tubulin destabilizer) with anticancer activity.

References: Prinz H, et al. N-benzoylated phenoxazines and phenothiazines: synthesis, antiproliferative activity, and inhibition of tubulin polymerization. J Med Chem. 2011 Jun 23;54(12):4247-63.

Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products

Product Promise

Promise
Molecular Weight (MW)367.85
Molecular FormulaC20H14ClNO2S
CAS No.105925-39-1
ProtocolIn VitroTubulin inhibitor 6 displays submicromolar antiproliferative activity
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.7185 mL13.5925 mL27.1850 mL54.3700 mL
5mM0.5437 mL2.7185 mL5.4370 mL10.8740 mL
10mM0.2718 mL1.3592 mL2.7185 mL5.4370 mL
20mM0.1359 mL0.6796 mL1.3592 mL2.7185 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.