TN-16

This product is for research use only, not for human use. We do not sell to patients.

TN-16
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
50mg$500To Be Confirmed
100mg$750To Be Confirmed
200mg$1125To Be Confirmed

Cat #: V16531 CAS #: 33016-12-5 Purity ≥ 99%

Description: TN-16 (TN16; NSC-239274) is a potent tubulin inhibitor (antitubulin/antimitotic agent) with anticancer activity.

References: Arai T. Inhibition of microtubule assembly in vitro by TN-16, a synthetic antitumor drug. FEBS Lett. 1983 May 8;155(2):273-6. 

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Molecular Weight (MW)306.36
Molecular FormulaC19H18N2O2
CAS No.33016-12-5
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.2641 mL16.3207 mL32.6413 mL65.2827 mL
5mM0.6528 mL3.2641 mL6.5283 mL13.0565 mL
10mM0.3264 mL1.6321 mL3.2641 mL6.5283 mL
20mM0.1632 mL0.8160 mL1.6321 mL3.2641 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.