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Verubulin hydrochloride (MPC-6827 hydrochloride)

This product is for research use only, not for human use. We do not sell to patients.

Verubulin hydrochloride (MPC-6827 hydrochloride)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$650Check With Us
250mg$1250Check With Us
500mg$1875Check With Us

Cat #: V28779 CAS #: 917369-31-4 Purity ≥ 99%

Description: Verubulin hydrochloride (MPC-6827 hydrochloride), the hydrochloride salt of verubulin, is a quinazoline-based and BBB (blood brain barrier) permeable microtubule-disrupting agent with potential antitumor activity.

References: Kasibhatla S, et al. MPC-6827: a small-molecule inhibitor of microtubule formation that is not a substrate for multidrug resistance pumps. Cancer Res. 2007 Jun 15;67(12):5865-71.

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Molecular Weight (MW)315.80
Molecular FormulaC17H18ClN3O
CAS No.917369-31-4
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.1666 mL15.8328 mL31.6656 mL63.3312 mL
5mM0.6333 mL3.1666 mL6.3331 mL12.6662 mL
10mM0.3167 mL1.5833 mL3.1666 mL6.3331 mL
20mM0.1583 mL0.7916 mL1.5833 mL3.1666 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.