6H05 TFA
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $980 | Check With Us |
| 250mg | $1750 | Check With Us |
| 500mg | $2625 | Check With Us |
: Cat #: V1571 CAS #: 2061344-88-3 Purity ≥ 98%
Description: 6H05 TFA (6H-05; 6 H05), the trifluoroacetic acd salt of 6H05, is a potent, covalent, selective and allosteric inhibitor of K-Ras (G12C) which is oncogenic.
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| Molecular Weight (MW) | 590.14 |
|---|---|
| Molecular Formula | C20H30ClN3O2S3.CF3COOH |
| CAS No. | 2061344-88-3 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 100 mg/mL (169.5 mM)r |
| Water: 100 mg/mL (169.5 mM)r | |
| Ethanol: 100 mg/mL (169.5 mM) | |
| Synonyms | 6 H 05 TFA; 6 H 05 TFA salt; 6H05 TFA; 6H05 TFA salt; 6-H-05 TFA; 6-H-05 TFA salt; K-Ras(G12C) inhibitor 6H05 |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.6945 mL | 8.4726 mL | 16.9451 mL | 33.8903 mL |
| 5mM | 0.3389 mL | 1.6945 mL | 3.3890 mL | 6.7781 mL |
| 10mM | 0.1695 mL | 0.8473 mL | 1.6945 mL | 3.3890 mL |
| 20mM | 0.0847 mL | 0.4236 mL | 0.8473 mL | 1.6945 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start)
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Volume(start)
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Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
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V1
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Concentration(final)
C2
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Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.