LDN-193189 2HCl

This product is for research use only, not for human use. We do not sell to patients.

LDN-193189 2HCl
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$950Check With Us
500mg$1425Check With Us
1g$2135Check With Us

Cat #: V3250 CAS #: 1435934-00-1 Purity ≥ 98%

Description: LDN193189 2HCl is the dihydrochloride salt of LDN193189, which is a highly potent and selective small molecule inhibitor of the BMP (bone morphogenetic protein ) signaling pathway.

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Product Promise

Promise
Molecular Weight (MW)479.4
Molecular FormulaC25H24Cl2N6
CAS No.1435934-00-1
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 1~20 mg/mL, vary from batch to batchr
Water: 50-100 mg/mLr
Ethanol: N/A
SMILES CodeC1(C2=C3N=CC(C4=CC=C(N5CCNCC5)C=C4)=CN3N=C2)=CC=NC6=CC=CC=C16.Cl.Cl
SynonymsDM3189 2HCl; DM-3189 2HCl; DM 3189 2HCl; LDN193189 2HCl; LDN 193189 2HCl; LDN-193189 2HCl
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.0859 mL10.4297 mL20.8594 mL41.7188 mL
5mM0.4172 mL2.0859 mL4.1719 mL8.3438 mL
10mM0.2086 mL1.0430 mL2.0859 mL4.1719 mL
20mM0.1043 mL0.5215 mL1.0430 mL2.0859 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.