Octreotide acetate

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
500mg	$750	Check With Us
1g	$1300	Check With Us
5g	$3510	Check With Us

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Cat #: V29289 CAS #: 79517-01-4 Purity ≥ 99%

Description: Octreotide acetate (SMS201-995; Sandostatin, SMS201995; Samilstin; Sandostatina; Octreotide-LAR; Longastatin), the acetate salt of Octreotide, is an octapeptide and somatostatin analogue acting as an agonist for sst2, sst3 and sst5 somatostatin receptors.

References: Wang M, et al. Pharmacokinetic and pharmacodynamic study of a phospholipid-based phase separation gel for once a month administration of octreotide. J Control Release. 2016 May 28;230:45-56.

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Physicochemical and Storage Information
Protocol
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Stock Solution Preparation
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Molecular Weight (MW)	1079.29
Molecular Formula	C51H70N10O12S2
CAS No.	79517-01-4

Protocol	In Vivo	Octreotide-treated groups show a significant reduction in the tumor volume when compared with saline group. Octreotide-PPSG (1.4 mg/kg, i.p.) shows greater antitumor effect than Octreotide-soln (100 μg/kg, i.p.). Octreotide-treatments results in significant inhibitory effect on the expression levels of SSTR2 and SSTR5 in primary HCC-bearing rats compared with the saline group. Octreotide-PPSG appears to inhibit the expression of SSTR2 and SSTR5 to a greater extent than that of Octreotide-soln treated group

These protocols are for reference only. InvivoChem does not independently validate these methods.

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	0.9265 mL	4.6327 mL	9.2654 mL	18.5307 mL
5mM	0.1853 mL	0.9265 mL	1.8531 mL	3.7061 mL
10mM	0.0927 mL	0.4633 mL	0.9265 mL	1.8531 mL
20mM	0.0463 mL	0.2316 mL	0.4633 mL	0.9265 mL

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.