Rotundine

This product is for research use only, not for human use. We do not sell to patients.

Rotundine
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
500mg$350Check With Us
1g$600Check With Us
5g$1560Check With Us

Cat #: V1264 CAS #: 483-14-7 Purity ≥ 98%

Description: Rotundine (also called L-THP or L-tetrahydropalmatine) is a naturally occuring alkaloid isolated from Corydalis rhizoma (a traditional Chinese medicinal plant) with analgesic activity.

References: Wang JB, et al. l-tetrahydropalamatine: a potential new medication for the treatment of cocaine addiction. Future Med Chem. 2012 Feb;4(2):177-86.

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Product Promise

Promise
Molecular Weight (MW)355.43
Molecular FormulaC21H25NO4
CAS No.483-14-7
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 8 mg/mL (22.5 mM)r
Water: <1 mg/mLr
Ethanol: <1 mg/mL
Synonyms(-)-Tetrahydropalmatine; L-Tetrahydropalmatine; Rotundine
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.8135 mL14.0675 mL28.1349 mL56.2699 mL
5mM0.5627 mL2.8135 mL5.6270 mL11.2540 mL
10mM0.2813 mL1.4067 mL2.8135 mL5.6270 mL
20mM0.1407 mL0.7034 mL1.4067 mL2.8135 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.