Pramipexole (SND-919)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 5g | $190 | In Stock |
| 10g | $320 | In Stock |
| 20g | $480 | In Stock |
: Cat #: V0046 CAS #: 104632-26-0 Purity ≥ 98%
Description: Pramipexole (also known as SND 919), an agonist of the Gαi-linked dopamine receptors D2, D3, and D4, is a potent dopamine agonist of the non-ergoline class.
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- Physicochemical and Storage Information
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- Related Biological Data
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- Quality Control Documentation
| Molecular Weight (MW) | 211.33 |
|---|---|
| Molecular Formula | C10H17N3S |
| CAS No. | 104632-26-0 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 42 mg/mL (198.7 mM)r |
| Water: <1 mg/mLr | |
| Ethanol: 42 mg/mL (198.7 mM) | |
| Synonyms | SND 919; SND-919; SND919; Pramipexole; Oprymea; Pramipexol; Pramipexolum |
| Protocol | In Vivo | Pramipexole (0.25-1 mg/kg; i.p.) significantly reduces the infarction volume in animals |
|---|---|---|
| Animal model | Pramipexole (0.25-1 mg/kg; i.p.) significantly reduces the infarction volume in animals) | |
| Dosages | 0.25 mg/kg, 1 mg/kg | |
| Administration | Intraperitoneal injection |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 4.7319 mL | 23.6597 mL | 47.3194 mL | 94.6387 mL |
| 5mM | 0.9464 mL | 4.7319 mL | 9.4639 mL | 18.9277 mL |
| 10mM | 0.4732 mL | 2.3660 mL | 4.7319 mL | 9.4639 mL |
| 20mM | 0.2366 mL | 1.1830 mL | 2.3660 mL | 4.7319 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.