Sumanirole maleate

This product is for research use only, not for human use. We do not sell to patients.

Sumanirole maleate
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$800Check With Us
250mg$1650Check With Us
500mg$2475Check With Us

Cat #: V15535 CAS #: 179386-44-8 Purity ≥ 99%

Description: Sumanirole maleate (U-95666E; PNU-95666), the maleate salt of Sumanirole, is a first-in-class and highly selective D2 receptor full agonist (ED50 = ~46 nM) with antiparkinsonian effects.

References: Arthur G. Romero, et al. Synthesis of the Selective D2 Receptor Agonist PNU-95666E from D-Phenylalanine Using a Sequential Oxidative Cyclization Strategy. J. Org. Chem. 1997, 62, 6582-6587

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Product Promise

Promise
Molecular Weight (MW)319.31
Molecular FormulaC15H17N3O5
CAS No.179386-44-8
ProtocolIn VitroSumanirole is a highly valuable tool compound for basic research to identify neurobiological mechanisms that are based on a dopamine D2-linked (vs. D1, D3, D4, and D5-linked) mechanism of action.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.1318 mL15.6588 mL31.3175 mL62.6351 mL
5mM0.6264 mL3.1318 mL6.2635 mL12.5270 mL
10mM0.3132 mL1.5659 mL3.1318 mL6.2635 mL
20mM0.1566 mL0.7829 mL1.5659 mL3.1318 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.