Phenothiazine (NSC2037; ENT38)

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
10g	$150	Check With Us
25g	$250	Check With Us
50g	$375	Check With Us

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Cat #: V1256 CAS #: 92-84-2 Purity ≥ 98%

Description: Phenothiazine (NSC 2037; ENT38; ENT 38; NSC-2037) is a potent dopamine-2 (D2) receptor antagonist used as antipsychotic medications for the treatment of schizophrenia and manifestations of psychotic disorders.

References: Mitchell SC, et, al. The toxicity of phenothiazine. Drug Metabol Drug Interact. 1994;11(3):201-35.

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Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	199.27
Molecular Formula	C12H9NS
CAS No.	92-84-2
Storage	-20℃ for 3 years in powder formr
Storage	-80℃ for 2 years in solvent
Solubility In Vitro	DMSO: 40 mg/mL (200.7 mM)r
	Water: <1 mg/mLr
	Ethanol: <1 mg/mL
Solubility In Vivo	Chemical Name: 10H-Phenothiazine InChi Key: WJFKNYWRSNBZNX-UHFFFAOYSA-N InChi Code: InChI=1S/C12H9NS/c1-3-7-11-9(5-1)13-10-6-2-4-8-12(10)14-11/h1-8,13H SMILES Code: C12=CC=CC=C1NC3=C(C=CC=C3)S2
Synonyms	ENT-38; Phenothiazine; NSC 2037; ENT38; ENT 38; NSC-2037 NSC2037

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	5.0183 mL	25.0916 mL	50.1832 mL	100.3663 mL
5mM	1.0037 mL	5.0183 mL	10.0366 mL	20.0733 mL
10mM	0.5018 mL	2.5092 mL	5.0183 mL	10.0366 mL
20mM	0.2509 mL	1.2546 mL	2.5092 mL	5.0183 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.